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the charges stemmed from gsk s promotion of the anti-depressants paxil paroxetine and wellbutrin bupropion for unapproved uses from 1998 2003, specifically as suitable for patients under the age of 18, and from its failure to report safety data about avandia rosiglitazone , both in violation of the federal food, drug, and cosmetic act.

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based on the assumption that the relationship between paroxetine s in vitro ki and its lack of effect on terfenadine s in vivo clearance predicts its effect on other 3a4 substrates, paroxetine s extent of inhibition of cyp3a4 activity is not likely to be of clinical significance.

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be sure to mention any of the following certain antipsychotics such as chlorpromazine, fluphenazine, perphenazine, prochlorperazine compro, procomp , thioridazine, trifluoperazine ; bupropion wellbutrin, zyban, others,in contrave ; cimetidine tagamet ; duloxetine cymbalta ; flecainide tambocor ; propafenone rythmol ; quinidine in nuedexta ; selective serotonin reuptake inhibitors ssris such as citalopram celexa , escitalopram lexapro , fluoxetine prozac, sarafem, selfemra, in symbyax , fluvoxamine luvox , paroxetine brisdelle, paxil, pexeva , and sertraline zoloft ; and tolazamide tolinase .

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